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Phosphofructokinase (PFK) Deficiency

Phosphofructokinase Deficiency, commonly called PFK Deficiency (or sometimes less accurately called just "PFK"), is an inherited disorder where an essential enzyme, phosphofructokinase, is deficient. This enzyme, PFK for short, is critical in the conversion of glucose to energy, particularly in red blood cells and muscle cells. Dogs who are deficient in PFK will have muscle and red blood cells that cannot supply their own energy needs, which becomes most apparent in times of stress or heavy exercise. Much of the time, during levels of low stress and exercise, they will have a lower-than-normal level of red blood cells ("persistent mild anemia"), which may not be as readily apparent and may not exhibit any visible symptoms. It is in times of stress and exercise that the condition would become obvious and likely demand veterinary attention.

Symptoms of Phosphofructokinase Deficiency
Most of the symptoms would appear after stress, exercise, heat, or excessive barking, and they include tiredness, weakness, apparent muscle cramps, pale gums, and high fever. One symptom that is often the identifying factor of the disease is dark-colored urine, caused by the breakdown of blood products.
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Read on! Check out:   Dog Health   |   Dog Nutrition   |   Training   |   Grooming   |   more articles
Recent Visitor Comments
Glen of Imaal Terrier
Recently we rescued of Glen of Imaal from our local SPCA. She is 4 yrs old and is a very focused little girl. A mind of her own, not real affectionate, but very loyal at the same time. She has trained me well.

Akita
I've owned 2 male Akitas. They've both been very healthy, low maintenance, friendly to humans, have lived with other pets but are NOT good with other males. Don't require a great deal of exercise.. A walk twice a day is plenty. Mine chew ice cubes after a walk. Neither of them showed any real interest in chewing anything else, but this has proven to keep their teeth and gums healthy and it's kind of funny, too. Can't sing their praises enough. Wonderful family membe

Coton de Tulear
My frenid Joan in My frenid Joan in Toronto was featured on Dogs With Jobs in Canada about 10 years ago. She had´╗┐ a standard poodle named Morgan as her narcolepsy service dog, and to our knowledge he was the first in the world. Joan now has Shaba as her service dog. Because the collapses in narcolepsy are actually paralysis (cataplexy) rather than sleep, Shaba's job is to drag her to a safe place when she's going to collapse, and stand over her and protect her while she's down. Was this

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Puppies due
Posted 3/15/2017
This litter is due in May we are expecting Solid Blues, blacks and formys...
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Featured Breed -

Australian Shepherd

The Australian Shepherd At a Glance
Recognized By AKC, CanKC, UKC, CKC, KCUK, FCI
Country of Origin United States
Life Expectancy 13 - 15 yrs
Height Range 20 - 23 in (M); 18 - 21 in (F)
Weight Range 50 - 65 lbs (M); 40 - 55 lbs (F)
Colors Red, Red Merle, Blue Merle, Black; with or without white markings, with or without tan/copper points
Trainability Excellent. Natural for obedience.
With Children Very good
With Animals Good
Climate Tolerates cold well
Indoor/Outdoor Enjoys indoor compaionship but needs lots of outdoor room
Exercise Reqd High. Needs plenty of outdoor exercise and interaction
Grooming Reqd Moderate, due to dense coat
Australian Shepherd Information
The founding registry for the breed is the Australian Shepherd Club of America. This organization is responsible for the development of the breed and breed standard, and they maintain their own registry and shows. The ASCA maintains a stringent code of ethics among members, so many respected, reputable breeders will dual-register with both ASCA and AKC.
Click to find:   Australian Shepherd Puppies For Sale   |   Australian Shepherd Breeders   |   Australian Shepherd Information

Dog Question of the Week

Some answers to last week's question:
Who is your favorite dog from TV or movies?
This Week's Question:
What is the best trick you have ever taught your dog?
Max (How the Grinch Stole Christmas)
Teresa from Waynesboro, VA, USA
Lassie
Aimee from Elk Falls, Kansas, USA
Asta, From The Thin Man Movie (1934)
Samantha from Riggins, South Carolina, USA
Dog Question of the Week
What is the best trick you have ever taught your dog?
Your first name
Your city
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